Семинар НУЛ ИВБ "Exact p-value calculation for high resolution Tandem Mass Spectrometry data"

On April 16, 2025 at 2:00 PM a seminar of the Laboratory on AI for Computational Biology will be held on the topic "Exact p-value calculation for high resolution Tandem Mass Spectrometry data".

Speaker: Kishankumar Bhimani, Researcher.  

Abstract: Kishan's research talk will highlights, how we identify peptides from high-resolution mass spectrometry data. First, a faster version of the XPV algorithm was developed, and speeding up run-time for peptide identification. Second, the XPV method was adapted to high-resolution data (HR-XPV), improving the accuracy of p-values and reducing false matches. Third, a new algorithm called SeVa was created to detect single amino acid variations, helping to find mutated peptides in complex samples. These advancements make peptide analysis more reliable, especially in large-scale proteomics and MS/MS studies.