School-conference "Information Technologies and Systems" 2019

Laboratory staff - conference participants

September 17-22 2019, the School-Conference "Information Technologies and Systems" was held in Perm. Researchers of the laboratory participated in the Bioinformatics section of the conference. Data analysis in molecular biology, bioinformatic algorithms, transcriptomics, regulation of gene expression, RNA secondary structure, chromatin 3D structure, functional annotation of genes and genomes, comparative genomics, molecular evolution were discussed.

The head of the laboratory, Maria Poptsova, made an oral presentation "Methods of data analysis applied to the spatial structure of DNA."

5 research trainees presented poster reports:

The relationship between DNA secondary structures, epigenetic markers and structural somatic mutations in cancer genomes (Anna Kurilovich)

Deep neural networks for recognition of Z-DNA regions and their patterns of association with histone tags (Nazar Beknazarov)

Recognition of general and tissue-specific patterns of association of quadruplexes and histone modifications by deep learning models (Arina Nostaeva)

 Chromatin Space Structure Prediction using Machine Learning (Michal Rosenwald)

Mutation signatures in genomes of the genus Brucella (Maria Volobueva)

Leading researcher of the laboratory Mikhail Gelfand was the head of the section.

Dmitry Svetlichny, a leading researcher, also attended the conference.

Furthermore, poster presentations were made by students working under the guidance of Maria Poptsova and Sergey Spirin:

The role of CpG methylation of quadruplexes in epigenetic regulation (Dmitry Konovalov, head - Maria Poptsova)

Determination of the location of nucleosomes in the genome of Saccharomyces cerevisiae using machine learning methods (Daria Afentieva, head - Maria Poptsova)

Estimation of the proportion of CpG dinucleotides under negative selection in the human genome using an evolution model based on Markov chains taking into account reverse substitutions (Vladislav Belousov, head - Sergey Spirin)