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International Laboratory of Bioinformatics

SOON

The laboratory was established in 2018 to advance the field of bioinformatics at the Faculty of Computer Science. The International Laboratory of Bioinformatics is actively engaged in the development and application of the most modern methods of machine learning and artificial intelligence for the analysis of omics molecular biology data.

The main areas of scientific activity of the laboratory are:

1. Fundamental studies of the role of secondary DNA structures and their relation to the epigenetic code. The practical application of research is aimed at developing drugs that control the work of flipons – secondary DNA structures that regulate the work of the genome. In particular, a potential cancer drug has been proposed that regulates the work of the genome by incorporating one of the flipons – Z-DNA.

2. Development of pipeline analysis of genomic sequencing data, genetic panels. Complete analysis from variant to phenotype. Since 2019, the laboratory has been interacting with medical institutions and pharmaceutical companies in this area of ​​activity.

3. Machine learning in bioinformatics. Work in this direction has been carried out since 2018. The laboratory cooperates with major industrial partners.

4. Genetic research in the field of cardiogenetics, focused on creating a catalog of mutations of patients with cardiovascular diseases. In 2020, the Consortium "Genetics of сardiovascular diseases" was created.

5. Development of AI systems in bioinformatics. Development of AI systems for predicting the diagnosis and course of diseases. Since 2020, the first systems for predicting the side effects of anticoagulants, antidepressants and antipsychotics have been made within the framework of this area of scientific activity of the laboratory. This direction finds application in pharmaceutical companies.

The results of the research work of the laboratory are published in Russian and international journals. Various scientific and educational events on the research topics are regularly held, such as scientific seminars on machine learning methods in bioinformatics, summer and winter schools on bioinformatics, round tables, conferences and the annual interdisciplinary forum of the "Genetics of сardiovascular diseases" Consortium. The International Laboratory of Bioinformatics is actively collaborating with leading world-class laboratories.

News

HSE University hosted an international mini-conference titled 'Search for new ways to develop Russian-Italian cooperation in the field of Biomedicine,' attended by scientists from both countries and HSE Rector Nikita Anisimov.
May 22
Maria Poptsova, Anton Vorobyov gave a report on the AI ​​prognostic system for predicting adverse outcomes in patients with myocardial infarction
April 25
We talked about cardiogenetics with the head of the International Bioinformatics Laboratory, Maria Poptsova, on Radio Mayak
April 05
The annual student school-conference “Information technologies and systems. Bioinformatics" ITIS(b), which was attended by more than 100 people from HSE, IITP RAS, Skoltech, Moscow State University, MIPT.
February 19
01/25/2024 laboratory staff took part in the scientific and practical conference “Tatiana’s Day” - elements of artificial intelligence in modern hematology"
January 25
Maria Poptsova, head of the international laboratory of bioinformatics at the Faculty of Computer Science of the National Research University Higher School of Economics, spoke on Radio Mayak in the “Physicists and Lyricists” section. "Developments".
December 21, 2023
On December 6, Sber held an R&D day
December 06, 2023
On November 30, 2023, the two-day II International Forum of Genomic and Biomedical Technologies “From Birth to Active Longevity” was held at Surgut State University.
December 06, 2023
On November 28, 2023, laboratory staff took part in the international conference ABZ-2023
November 28, 2023
As part of the strategic session “Development and development of cardiac diagnostic products: from sequencing to medical practice,” Maria Poptsova made a report “Modern trends and challenges in the domestic cardiogenetics market - comparison with global experience.”
October 09, 2023
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