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Centre for Biomedical Research and Technologies

Centre for Biomedical Research and Technologies was established within the the International Laboratory of Bioinformatics at the Faculty of Computer Science. The centre is actively developing and applying cutting-edge machine learning and artificial intelligence methods to analyze omics data in molecular biology.

The main areas of scientific activity of the centre are:

1. Fundamental studies of the role of secondary DNA structures and their relation to the epigenetic code. The practical application of research is aimed at developing drugs that control the work of flipons – secondary DNA structures that regulate the work of the genome. In particular, a potential cancer drug has been proposed that regulates the work of the genome by incorporating one of the flipons – Z-DNA.

2. Development of pipeline analysis of genomic sequencing data, genetic panels. Complete analysis from variant to phenotype. Since 2019, the centre has been interacting with medical institutions and pharmaceutical companies in this area of ​​activity.

3. Machine learning in bioinformatics. Work in this direction has been carried out since 2018. Centre cooperates with major industrial partners.

4. Genetic research in the field of cardiogenetics, focused on creating a catalog of mutations of patients with cardiovascular diseases. In 2020, the Consortium "Genetics of сardiovascular diseases" was created.

5. Development of AI systems in bioinformatics. Development of AI systems for predicting the diagnosis and course of diseases. Since 2020, the first systems for predicting the side effects of anticoagulants, antidepressants and antipsychotics have been made within the framework of this area of scientific activity of Centre. This direction finds application in pharmaceutical companies.

The results of the research work of Centre are published in Russian and international journals. Various scientific and educational events on the research topics are regularly held, such as scientific seminars on machine learning methods in bioinformatics, summer and winter schools on bioinformatics, round tables, conferences and the annual interdisciplinary forum of the "Genetics of сardiovascular diseases" Consortium. Centre for Biomedical Research and Technologies is actively collaborating with leading world-class laboratories and centres alike.

News

On Februrary 27th, department heads and vice-heads of the HSE AI and Digital Science Institute participated in Strategy Workshop, titled "Joined Future".
March 04
Research (scientific) structural units of HSE University planning to conduct joint research with foreign universities and research centres are invited to take part in the competition.
March 02
The annual Winter School-Conference on Bioinformatics was held at the Voronovo UC of the National Research University Higher School of Economics with the participation of the co-organizer, the International Laboratory of Statistical and Computational Genomics, which was attended by more than 150 people from the HSE, IITP RAS, Skoltech, Moscow State University, and MIPT. The event was sponsored by "Genotek".
February 16
Researchers at the HSE AI Research Centre have developed an AI model that opens up new possibilities for the diagnosis and treatment of serious diseases, including brain cancer and neurodegenerative disorders. Using artificial intelligence, the team studied G-quadruplexes—structures that play a crucial role in cellular function and in the development of organs and tissues. The findings have been published in Scientific Reports.
January 20
On October 24-25, 2025, HSE University held the 4th Fall into ML conference, bringing together researchers, students, and industry professionals working at the forefront of machine learning and AI.
October 25, 2025
At an international foresight workshop on artificial intelligence held at HSE University, Russian and foreign scholars discussed the trends and challenges arising from the rapid development of AI.
September 15, 2025
The annual Interdisciplinary Forum "Bioinformatics and Cardiogenetics: Realities of 2025" was held on September 8-9. It focused on the project "Machine Learning Technologies in Predicting Outcomes of Acute Coronary Syndrome," which is being implemented within the Mirror Lab.
September 09, 2025
The International Bioinformatics Laboratory of the HSE Faculty of Computer Science held a summer school titled "Cardiogenetics: From Sequencing to Cardiopanel Development." Eighteen participants, including physicians, biologists, and IT professionals, participated.
August 28, 2025
The Summer School on Machine Learning in Bioinformatics was held from August 25-27 at 11 Pokrovsky Boulevard. Speakers included: Maria Poptsova, Head of the International Bioinformatics Laboratory at the Faculty of Computer Science at the Higher School of Economics Alexander Rakitko, International Bioinformatics Laboratory at the Faculty of Computer Science at the Higher School of Economics, Genotek Vladimir Shchur, International Laboratory of Statistical and Computational Genomics at the Faculty of Computer Science at the Higher School of Economics, and others
August 27, 2025
The International Bioinformatics Laboratory took part in the Moscow Conference on Computational Molecular Biology on July 30 – August 3, 2025 at Skoltech.
July 30, 2025
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