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VII international conference "Mathematical biology and bioinformatics", Pushchino, October 14-19 2018

The laboratory staff Otabek Matkarimov and Denis Polivoda made an oral presentation at the international conference at the Institute of mathematical problems of biology RAS, Pushchino.

VII international conference "Mathematical biology and bioinformatics", Pushchino, October 14-19 2018

At the VII International conference "Mathematical biology and bioinformatics", which was held at the Institute of mathematical problems of biology of the RAS Pushchino from 14 to 19 October 2018, the staff of the Laboratory of Bioinformatics Otabek Matkarimov and Denis Polivoda D. E. made an oral report "Search patterns of Association between the functional elements of the genome."

Speakers at the conference raised the issue of pattern search and analysis of genomic data. At the moment, the existing pattern search programs have significant limitations, most of which are implemented to work in the Unix system, there is no graphical interface, and the programs themselves are difficult to use.

To solve this problem, the laboratory began to develop a cross-platform program with a graphical user interface that runs in a browser on any operating system that accepts two genomic annotation files in the format .bed, visualize the distribution of functional elements in the form of densities at the level of chromosomes and searches for patterns of Association between the two investigated genomic elements.

The found patterns are visualized, and information about their location is given in the form of a list. This program is designed to solve a wide class of bio-format problems of finding patterns of Association between different functional genome annotations.

Publication: 
Matkarimov O. O., Polivoda D. E., Poptsova M. S. "Search for patterns of Association between functional elements of the genome". Reports Of the international conference “Mathematical biology and bioinformatics”. Ed. by V. D. Lakhno. Volume 7.  Pushchino: IMPB RAS, 2018. Article No e51. doi: 10.17537/icmbb18.82