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International Laboratory of Bioinformatics

SOON

The laboratory was established in 2018 to advance the field of bioinformatics at the Faculty of Computer Science. The International Laboratory of Bioinformatics is actively engaged in the development and application of the most modern methods of machine learning and artificial intelligence for the analysis of omics molecular biology data.

The main areas of scientific activity of the laboratory are:

1. Fundamental studies of the role of secondary DNA structures and their relation to the epigenetic code. The practical application of research is aimed at developing drugs that control the work of flipons – secondary DNA structures that regulate the work of the genome. In particular, a potential cancer drug has been proposed that regulates the work of the genome by incorporating one of the flipons – Z-DNA.

2. Development of pipeline analysis of genomic sequencing data, genetic panels. Complete analysis from variant to phenotype. Since 2019, the laboratory has been interacting with medical institutions and pharmaceutical companies in this area of ​​activity.

3. Machine learning in bioinformatics. Work in this direction has been carried out since 2018. The laboratory cooperates with major industrial partners.

4. Genetic research in the field of cardiogenetics, focused on creating a catalog of mutations of patients with cardiovascular diseases. In 2020, the Consortium "Genetics of сardiovascular diseases" was created.

5. Development of AI systems in bioinformatics. Development of AI systems for predicting the diagnosis and course of diseases. Since 2020, the first systems for predicting the side effects of anticoagulants, antidepressants and antipsychotics have been made within the framework of this area of scientific activity of the laboratory. This direction finds application in pharmaceutical companies.

The results of the research work of the laboratory are published in Russian and international journals. Various scientific and educational events on the research topics are regularly held, such as scientific seminars on machine learning methods in bioinformatics, summer and winter schools on bioinformatics, round tables, conferences and the annual interdisciplinary forum of the "Genetics of сardiovascular diseases" Consortium. The International Laboratory of Bioinformatics is actively collaborating with leading world-class laboratories.

News

The annual student school-conference “Information technologies and systems. Bioinformatics" ITIS(b), which was attended by more than 100 people from HSE, IITP RAS, Skoltech, Moscow State University, MIPT.
February 19
01/25/2024 laboratory staff took part in the scientific and practical conference “Tatiana’s Day” - elements of artificial intelligence in modern hematology"
January 25
Maria Poptsova, head of the international laboratory of bioinformatics at the Faculty of Computer Science of the National Research University Higher School of Economics, spoke on Radio Mayak in the “Physicists and Lyricists” section. "Developments".
December 21, 2023
On November 30, 2023, the two-day II International Forum of Genomic and Biomedical Technologies “From Birth to Active Longevity” was held at Surgut State University.
December 06, 2023
On November 28, 2023, laboratory staff took part in the international conference ABZ-2023
November 28, 2023
As part of the strategic session “Development and development of cardiac diagnostic products: from sequencing to medical practice,” Maria Poptsova made a report “Modern trends and challenges in the domestic cardiogenetics market - comparison with global experience.”
October 09, 2023
On September 28-29, the International Laboratory of Bioinformatics of the National Research University Higher School of Economics together with the Scientific and Educational Center of the Medical Institute of the Khanty-Mansiysk Autonomous Okrug - Ugra "Surgut State University" for the purpose of implementing the project "Mirror Laboratories" held a sectional session "Cardiovascular continuum: from ACS to CHF"
October 02, 2023
One of the winning projects of a competition held by HSE University’s Mirror Laboratories last June focuses on the use of machine learning technologies to predict the outcomes of acute coronary syndrome. It is implemented by HSE University’s International Laboratory of Bioinformatics together with the Research and Educational Centre of the Medical Institute at Surgut State University. Maria Poptsova, Head of the International Laboratory of Bioinformatics and Associate Professor at HSE University’s Faculty of Computer Science, talks about how this joint project originated, how it will help patients, and how work to implement it will be organised.
September 25, 2023
On September 4-5, the annual Interdisciplinary Forum “Cardiogenetics and Bioinformatics: Realities 2023” was held at the Higher School of Economics.
September 15, 2023
The Continuing Professional Development Centre of the HSE Faculty of Computer Science has recently hosted the summer school 'Cardiogenetics: From Sequencing to Constructing a Cardio Panel'. The school programme was co-organised by the Russian Academy of Sciences' Institute of Analytical Instrumentation and Institute of Spectroscopy and the Syntol company.
September 15, 2023
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