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International Laboratory of Bioinformatics

SOON

The laboratory was established in 2018 to advance the field of bioinformatics at the Faculty of Computer Science. The International Laboratory of Bioinformatics is actively engaged in the development and application of the most modern methods of machine learning and artificial intelligence for the analysis of omics molecular biology data.

The main areas of scientific activity of the laboratory are:

1. Fundamental studies of the role of secondary DNA structures and their relation to the epigenetic code. The practical application of research is aimed at developing drugs that control the work of flipons – secondary DNA structures that regulate the work of the genome. In particular, a potential cancer drug has been proposed that regulates the work of the genome by incorporating one of the flipons – Z-DNA.

2. Development of pipeline analysis of genomic sequencing data, genetic panels. Complete analysis from variant to phenotype. Since 2019, the laboratory has been interacting with medical institutions and pharmaceutical companies in this area of ​​activity.

3. Machine learning in bioinformatics. Work in this direction has been carried out since 2018. The laboratory cooperates with major industrial partners.

4. Genetic research in the field of cardiogenetics, focused on creating a catalog of mutations of patients with cardiovascular diseases. In 2020, the Consortium "Genetics of сardiovascular diseases" was created.

5. Development of AI systems in bioinformatics. Development of AI systems for predicting the diagnosis and course of diseases. Since 2020, the first systems for predicting the side effects of anticoagulants, antidepressants and antipsychotics have been made within the framework of this area of scientific activity of the laboratory. This direction finds application in pharmaceutical companies.

The results of the research work of the laboratory are published in Russian and international journals. Various scientific and educational events on the research topics are regularly held, such as scientific seminars on machine learning methods in bioinformatics, summer and winter schools on bioinformatics, round tables, conferences and the annual interdisciplinary forum of the "Genetics of сardiovascular diseases" Consortium. The International Laboratory of Bioinformatics is actively collaborating with leading world-class laboratories.

News

At an international foresight workshop on artificial intelligence held at HSE University, Russian and foreign scholars discussed the trends and challenges arising from the rapid development of AI.
September 15
The annual Interdisciplinary Forum "Bioinformatics and Cardiogenetics: Realities of 2025" was held on September 8-9. It focused on the project "Machine Learning Technologies in Predicting Outcomes of Acute Coronary Syndrome," which is being implemented within the Mirror Lab.
September 09
The International Bioinformatics Laboratory of the HSE Faculty of Computer Science held a summer school titled "Cardiogenetics: From Sequencing to Cardiopanel Development." Eighteen participants, including physicians, biologists, and IT professionals, participated.
August 28
The Summer School on Machine Learning in Bioinformatics was held from August 25-27 at 11 Pokrovsky Boulevard. Speakers included: Maria Poptsova, Head of the International Bioinformatics Laboratory at the Faculty of Computer Science at the Higher School of Economics Alexander Rakitko, International Bioinformatics Laboratory at the Faculty of Computer Science at the Higher School of Economics, Genotek Vladimir Shchur, International Laboratory of Statistical and Computational Genomics at the Faculty of Computer Science at the Higher School of Economics, and others
August 27
The International Bioinformatics Laboratory took part in the Moscow Conference on Computational Molecular Biology on July 30 – August 3, 2025 at Skoltech.
July 30
The annual All-Russian scientific and practical conference "CARDIOLOGY ON THE MARCH 2025" was held on June 4-6, 2025 at the Federal State Budgetary Institution "NMITsK named after academician E.I. Chazov" of the Ministry of Health of the Russian Federation.
June 04
On May 15-17, 2025, the VIII St. Petersburg Medical Innovation Forum with international participation was held in the Almazovsky Cardiology Center in St. Petersburg.
May 15
On April 10, 2025, Maria Poptsova, Head of the International Laboratory of Bioinformatics at the Faculty of Computer Science at the National Research University Higher School of Economics, spoke at a meeting of the Faculty of Computer Science with a report entitled “Cardiogenetics: A Step Towards Personalized Medicine in the 21st Century”
April 10
On April 8, 2025, Nazar Beknazarov, a postgraduate student at the International Laboratory of Bioinformatics, Faculty of Computer Science, HSE, took part in the International Conference "Parallel Computing Technologies 2025" (PCT 2025), where he presented a report "Optimizing Computational Infrastructure for LLMs in Bioinformatics: A Case Study".
April 08
The annual Winter School-Conference on Bioinformatics was held at the Voronovo UC of the National Research University Higher School of Economics with the participation of the co-organizer, the International Laboratory of Statistical and Computational Genomics, which was attended by more than 100 people from the HSE, IITP RAS, Skoltech, Moscow State University, and MIPT.
February 27
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